Description

5-(1-Phenylethyl)-5-Propionyloxybarbituric Acid is a specialized barbiturate derivative of significant interest in advanced pharmaceutical synthesis. This compound serves as a critical intermediate for the development of novel therapeutic agents and for research into central nervous system (CNS) activity. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and pharmacology studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and modify CNS activity.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the mechanism of action of GABAA receptor modulators.
• Process Development: Utilized in scaling up and optimizing synthetic routes for complex organic molecules.

Basic Information

Product Name	5-(1-Phenylethyl)-5-Propionyloxybarbituric Acid
CAS No.	37431-38-2
Molecular Formula	C15H16N2O5
Molecular Weight	304.30 g/mol
Synonyms	5-(α-Methylbenzyl)-5-(propionyloxy)barbituric Acid; 5-(1-Phenylethyl)-5-(propionyloxy)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Propionyloxy-5-(1-phenylethyl)barbituric Acid; NSC 113928; Barbituric Acid, 5-(1-phenylethyl)-5-(propionyloxy)-
EINECS	Contact for details

Quality Control

Our 5-(1-Phenylethyl)-5-Propionyloxybarbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.