Description

(Pivaloyloxy)Methyl Butyrate CAS NO 37380-45-3 is a specialized organic ester compound, also known as pivmecillinam intermediate. This high-purity chemical building block is critical for ensuring the quality and efficacy of the final active pharmaceutical ingredient. It is primarily required by pharmaceutical manufacturers and advanced fine chemical synthesis facilities for the production of specific β-lactam antibiotics.

Application

• Key Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of pivmecillinam, an orally active prodrug of mecillinam.
• Antibiotic Production: Used in the manufacturing process of penicillin-class antibiotics for the treatment of bacterial infections.
• Fine Chemical Synthesis: Employed in research and development for creating novel ester-based compounds and prodrug molecules.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes within GMP-compliant production environments.

Basic Information

Item	Details
Product Name	(Pivaloyloxy)Methyl Butyrate
CAS No.	37380-45-3
Molecular Formula	C11H20O4
Molecular Weight	216.28 g/mol
Synonyms	Pivmecillinam Intermediate; Butanoic acid, [(2,2-dimethyl-1-oxopropoxy)methyl] ester; Pivaloyloxymethyl butyrate; Amdinocillin Pivoxil Intermediate; Mecillinam Pivoxil Precursor; RO 10-9070/001 (developmental code); Pivampicillin related compound
EINECS	Contact for details

Quality Control

Our (Pivaloyloxy)Methyl Butyrate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided and can be tailored to meet specific customer or regulatory requirements (e.g., ICH guidelines).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.