Description

α,4-Bis(Trimethylsiloxy)Benzeneacetic Acid Trimethylsilyl Ester is a high-purity, multi-functional organosilicon intermediate of significant synthetic value. This compound is prized for its role as a versatile building block in advanced organic synthesis, particularly for introducing protected functional groups. It is primarily utilized by research and development chemists, as well as process development teams, in the pharmaceutical, agrochemical, and specialty chemical industries for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially those requiring silyl-protected carboxylic acid or phenol functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents and herbicides where its silicon-based protecting groups offer selective reactivity.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialized silicon-containing polymers and advanced organic materials.
• Organic Synthesis Reagent: Employed in laboratory-scale and pilot-scale organic reactions, including cross-coupling and condensation reactions, where its trimethylsilyl groups provide stability and controlled deprotection.
• Chemical Research: A valuable reagent for academic and industrial research in methodology development and the synthesis of novel chemical entities.

Basic Information

Product Name	α,4-Bis(Trimethylsiloxy)Benzeneacetic Acid Trimethylsilyl Ester
CAS No.	37148-64-4
Molecular Formula	C17H32O4Si3
Molecular Weight	384.70 g/mol
Synonyms	2-(4-Bis(trimethylsiloxy)phenyl)acetic Acid Trimethylsilyl Ester; Benzeneacetic Acid, α,4-bis(trimethylsiloxy)-, Trimethylsilyl Ester; (4-Hydroxyphenyl)acetic Acid Tris(trimethylsilyl) Ether; Tris(trimethylsilyl) 4-Hydroxyphenylacetate; TMS-protected 4-Hydroxyphenylacetic Acid; α,4-Bis-O-TMS Phenylacetic Acid TMS Ester
EINECS	Contact for details

Quality Control

Our α,4-Bis(Trimethylsiloxy)Benzeneacetic Acid Trimethylsilyl Ester is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.