Description

2,4,6-Triisopropylbenzene-Sulfonyl Azide is a specialized sulfonyl azide reagent, a key intermediate in organic synthesis. Its primary value lies in its role as a versatile precursor for generating nitrenes, enabling critical transformations such as aziridination and C–H amination. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking efficient routes to nitrogen-containing compounds.

Application

• Nitrene Precursor in Organic Synthesis: Used to generate reactive nitrene species for the synthesis of aziridines and other N-heterocycles.
• C–H Amination Reactions: Enables the direct functionalization of inert C–H bonds to form C–N bonds, a valuable step in complex molecule construction.
• Polymer Modification: Employed in the cross-linking and functionalization of polymers to introduce azide or amine groups.
• Pharmaceutical Intermediate: Serves as a building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides containing nitrogen-based functional groups.
• Click Chemistry: Can be utilized in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions after appropriate transformation.
• Material Science Research: Applied in the surface functionalization of nanomaterials and the creation of novel organic frameworks.

Basic Information

Item	Details
Product Name	2,4,6-Triisopropylbenzene-Sulfonyl Azide
CAS No.	36982-84-0
Molecular Formula	C15H23N3O2S
Molecular Weight	309.43 g/mol
Synonyms	Trisyl azide; 2,4,6-Triisopropylbenzenesulfonyl azide; 2,4,6-Triisopropylphenylsulfonyl azide; TipSA; Trisyl azide reagent; 1,3,5-Triisopropyl-2-azidosulfonylbenzene; Benzenesulfonyl azide, 2,4,6-triisopropyl-; Azidotris(propan-2-yl)benzenesulfonate
EINECS	Contact for details

Quality Control

Our 2,4,6-Triisopropylbenzene-Sulfonyl Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its nature as an organic azide, store separately from incompatible materials and avoid shock, friction, and rapid temperature changes.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.