Description

(3-Bromophenoxy)Trimethylsilane CAS NO 36971-28-5 is a high-purity organosilicon intermediate featuring a brominated aromatic ether moiety protected by a trimethylsilyl group. This compound is valued for its dual functionality, serving as a versatile building block in advanced organic synthesis where precise control over molecular architecture is critical. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty materials industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing the 3-bromophenoxy moiety into target molecules.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromophenoxy group imparts specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds.
• Polymer Modification: Employed to functionalize polymers and resins, enhancing properties like thermal stability or introducing reactive sites for further cross-linking.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions such as Suzuki, Heck, or Sonogashira couplings due to the reactive bromine atom.
• Protecting Group Strategy: The trimethylsilyl group can act as a protective group for the phenol oxygen, allowing for selective reactions elsewhere on the molecule.
• Ligand Synthesis: Useful in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(3-Bromophenoxy)Trimethylsilane
CAS No.	36971-28-5
Molecular Formula	C9H13BrOSi
Molecular Weight	245.19 g/mol
Synonyms	Trimethyl(3-bromophenoxy)silane; 3-Bromophenoxytrimethylsilane; Silane, trimethyl(3-bromophenoxy)-; (3-Bromophenoxy)trimethylsilicon; 1-Bromo-3-(trimethylsilyloxy)benzene; m-Bromophenoxytrimethylsilane; 3-Bromo-1-(trimethylsilyloxy)benzene; Phenol, 3-bromo-, trimethylsilyl ether
EINECS	Contact for details

Quality Control

Our (3-Bromophenoxy)Trimethylsilane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.