Description

2-Bromo-4-hydroxypyridine is a versatile brominated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals, where precise functionalization is required.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	2-Bromo-4-hydroxypyridine
CAS No.	36953-40-9
Molecular Formula	C5H4BrNO
Molecular Weight	173.99 g/mol
Synonyms	4-Hydroxy-2-bromopyridine; 2-Bromo-4-pyridinol; 2-Bromo-4(1H)-pyridinone; 4-Pyridinol, 2-bromo-; 2-Bromo-4-hydroxypyridine; 2-Bromopyridin-4-ol; 4-Hydroxy-2-bromopyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-hydroxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.