Description

1-Oxaspiro[2.4]heptane-2-carbonitrile (6Ci,9Ci) is a specialized spirocyclic nitrile compound that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique spirocyclic oxirane structure makes it a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This high-purity intermediate is essential for medicinal chemists and process development scientists working on novel active ingredients, where precise stereochemistry and functional group compatibility are critical.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its spirocyclic framework for enhanced biological activity.
• Material Science Research: Serves as a precursor for functional polymers and advanced materials with specific optical or electronic properties.
• Asymmetric Catalysis: Employed as a ligand precursor or a substrate in catalytic reactions to induce chirality in target molecules.
• Fine Chemical Production: Integral to multi-step synthetic routes for high-value specialty chemicals and flavors & fragrances.
• Academic & R&D Laboratories: A critical reagent for methodological development and exploring new chemical spaces in organic synthesis.

Basic Information

Item	Details
Product Name	1-Oxaspiro[2.4]heptane-2-carbonitrile (6Ci,9Ci)
CAS No.	36929-35-8
Molecular Formula	C7H9NO
Molecular Weight	123.15 g/mol
Synonyms	1-Oxaspiro[2.4]heptane-2-carbonitrile; 2-Cyano-1-oxaspiro[2.4]heptane; 1-Oxaspiro[2.4]heptane-2-carbonitrile (6CI,9CI); Oxirane-2-carbonitrile, 3-spiro[2.4]heptane-; 3-Spiro[2.4]heptaneoxirane-2-carbonitrile; 2-Oxaspiro[3.4]octane-3-carbonitrile (isomer); Spiro[2.4]heptane-1,2-epoxide-2-carbonitrile
EINECS	Contact for details

Quality Control

Every batch of 1-Oxaspiro[2.4]heptane-2-carbonitrile is produced and tested under strict quality management systems to ensure consistency and reliability for your critical R&D and production processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our commitment to high-purity standards ensures this intermediate meets the rigorous demands of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to the reactive nature of the nitrile and oxirane functional groups, it is recommended to store under an inert atmosphere for long-term stability and to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.