Description

Ethyl 2-Amino-5,6-Dihydro-4H-4,7-Ethanothieno[2,3-B]Pyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthesis pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other specialized therapeutic areas.
• Organic Synthesis Building Block: Used in research and development for constructing complex polycyclic and fused-ring heterocyclic systems.
• Medicinal Chemistry Research: Employed in the discovery and optimization of new chemical entities (NCEs) due to its unique thienopyridine core structure.
• Fine Chemical Production: Serves as a specialized intermediate in the multi-step synthesis of high-value, low-volume fine chemicals and agrochemicals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant API production.

Basic Information

Product Name	Ethyl 2-Amino-5,6-Dihydro-4H-4,7-Ethanothieno[2,3-B]Pyridine-3-Carboxylate
CAS No.	36860-49-8
Molecular Formula	C14H18N2O2S
Molecular Weight	278.37 g/mol
Synonyms	Ethyl 2-Amino-4,7-ethano-4,5,6,7-tetrahydrothieno[2,3-b]pyridine-3-carboxylate; 2-Amino-4,7-ethano-4,5,6,7-tetrahydrothieno[2,3-b]pyridine-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-2-amino-4,7-ethano-4,5,6,7-tetrahydrothieno[2,3-b]pyridine; 2-Amino-4,7-ethano-4,5,6,7-tetrahydrothieno[2,3-b]pyridine-3-carboxylate Ethyl Ester; 36860-49-8; Thienopyridine Derivative; AETP Intermediate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Amino-5,6-Dihydro-4H-4,7-Ethanothieno[2,3-B]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality commitment supports applications requiring high standards, including cGMP manufacturing for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.