Description

(E)-3-Benzo[1,3]Dioxol-5-Yl-1-(4-Bromophenyl)Prop-2-En-1-One is a high-purity, synthetic chalcone derivative characterized by its distinct molecular structure featuring a benzodioxole and a bromophenyl moiety. This compound is valued as a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily sought by research institutions and chemical manufacturers engaged in the development of novel bioactive molecules, including potential therapeutic agents and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for anti-inflammatory, anticancer, or CNS-active compounds.
• Organic Synthesis Building Block: Utilized in various coupling reactions, cyclizations, and as a scaffold for constructing more complex heterocyclic compounds due to its reactive α,β-unsaturated ketone (enone) group.
• Chemical Research & Development: Employed in academic and industrial R&D settings for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Material Science Precursor: Potential use in the development of organic semiconductors, nonlinear optical materials, or advanced polymers where its conjugated system is beneficial.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	(E)-3-Benzo[1,3]Dioxol-5-Yl-1-(4-Bromophenyl)Prop-2-En-1-One
CAS No.	36716-01-5
Molecular Formula	C16H11BrO3
Molecular Weight	331.16 g/mol
Synonyms	(E)-1-(4-Bromophenyl)-3-(benzo[d][1,3]dioxol-5-yl)prop-2-en-1-one; 3,4-Methylenedioxy-4'-bromochalcone; 4'-Bromo-3,4-methylenedioxychalcone; (E)-3-(1,3-Benzodioxol-5-yl)-1-(4-bromophenyl)-2-propen-1-one; Chalcone, 4'-bromo-3,4-methylenedioxy-; 36716-01-5; 4'-Bromopiperonyl chalcone
EINECS	Contact for details

Quality Control

Our (E)-3-Benzo[1,3]Dioxol-5-Yl-1-(4-Bromophenyl)Prop-2-En-1-One is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.