Description

2-(2-Pyrrolidinylidene)-Acetic Acid Methyl Ester is a versatile heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its unique pyrrolidine-based structure, which is a key motif in the development of pharmaceuticals and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrrolidine or proline-like structures for neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators where the pyrrolidine ring enhances biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of dyes, pigments, and other performance chemicals requiring specific heterocyclic frameworks.
• Academic and Industrial Research: A valuable reagent for methodological development in organic chemistry, including cyclization and annulation reactions.

Basic Information

Product Name	2-(2-Pyrrolidinylidene)-Acetic Acid Methyl Ester
CAS No.	36625-47-5
Molecular Formula	C7H11NO2
Molecular Weight	141.17 g/mol
Synonyms	Methyl 2-(pyrrolidin-2-ylidene)acetate; 2-(2-Pyrrolidinylidene)acetic acid methyl ester; Methyl (2-pyrrolidinylidene)acetate; 2-Pyrrolidinylideneacetic acid methyl ester; 2-(Pyrrolidin-2-ylidene)acetic acid methyl ester; Methyl 2-(2-pyrrolidinylidene)acetate; 36625-47-5
EINECS	Contact for details

Quality Control

Our 2-(2-Pyrrolidinylidene)-Acetic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, impurity profile, and physical characteristics. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliable supply for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and organic solvents. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Light yellow to yellow liquid / solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.