Description

2-(4-Chlorobenzyl)Acetoacetic Acid Ethyl Ester is a versatile and high-purity organic intermediate essential for advanced chemical synthesis. This compound is valued for its reactive β-ketoester functionality, which serves as a key building block for constructing complex molecular architectures. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with chlorobenzyl or heterocyclic structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, leveraging its reactive site for constructing pesticidal molecules.
• Organic Synthesis Building Block: Employed in Claisen condensations, Michael additions, and other C-C bond-forming reactions to create complex organic molecules in R&D laboratories.
• Fine Chemical Production: Serves as a starting material for dyes, pigments, and other specialty chemicals requiring precise molecular frameworks.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of novel polymeric materials.

Basic Information

Product Name	2-(4-Chlorobenzyl)Acetoacetic Acid Ethyl Ester
CAS No.	36600-72-3
Molecular Formula	C₁₃H₁₅ClO₃
Molecular Weight	254.71 g/mol
Synonyms	Ethyl 2-(4-Chlorobenzyl)-3-oxobutanoate; Ethyl (4-Chlorobenzyl)acetoacetate; 3-Oxobutanoic acid, 2-[(4-chlorophenyl)methyl]-, ethyl ester; Acetoacetic acid, (p-chlorobenzyl)-, ethyl ester; Ethyl 2-(p-Chlorobenzyl)acetoacetate; 2-(4-Chlorobenzyl)-3-oxobutyric acid ethyl ester; Ethyl 4-Chlorobenzylacetoacetate
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorobenzyl)Acetoacetic Acid Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.