Description

[1-[[(Trimethylsilyl)Oxy]Methyl]Ethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester is a highly specialized organosilicon-phosphonate derivative, valued for its unique bifunctional reactivity as both a silylating agent and a phosphonate precursor. This compound is critical for advanced synthetic chemistry, enabling the precise modification of substrates and the construction of complex molecular architectures. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for applications requiring controlled functional group protection and introduction.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing phosphonate or protected phosphate functionalities.
• Agrochemical Synthesis: Serves as a key building block for creating advanced herbicides, fungicides, and plant growth regulators with enhanced activity.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphonate-based ligands for metal catalysis and organocatalysis.
• Surface Modification Agent: Utilized to functionalize silica, metal oxides, and other inorganic surfaces to alter wettability, adhesion, or catalytic properties.
• Polymer & Materials Science: Acts as a monomer or cross-linking agent in the development of specialty polymers, resins, and flame-retardant materials.
• Protecting Group Chemistry: Provides a robust trimethylsilyl (TMS) protecting group for hydroxyl and phosphonic acid functionalities in multi-step syntheses.

Basic Information

Item	Detail
Product Name	[1-[[(Trimethylsilyl)Oxy]Methyl]Ethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester
CAS No.	36449-17-9
Molecular Formula	C18H48O8P2Si5
Molecular Weight	594.99 g/mol
Synonyms	Bis(trimethylsilyl) [1-[[(trimethylsilyl)oxy]methyl]ethylenebis(oxy)]bis(phosphonate); Ethylene Glycol Bis[(bis(trimethylsilyl)phosphonate)] TMS Ether; Phosphonic Acid, P,P'-[1-[[(Trimethylsilyl)oxy]methyl]-1,2-ethanediyl] P,P,P',P'-tetrakis(trimethylsilyl) Ester; TMS-Protected Ethylene Glycol Bisphosphonate; Tetrakis(trimethylsilyl) Ethylene Glycol Bisphosphonate
EINECS	Contact for details

Quality Control

Our production of [1-[[(Trimethylsilyl)Oxy]Methyl]Ethylenebis(Oxy)]Bis[Phosphonic Acid Bis(Trimethylsilyl)] Ester adheres to stringent internal quality standards to ensure batch-to-batch consistency and purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profile. We are committed to meeting the specific purity requirements of our clients, with capabilities for producing custom grades.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.