Description

4-Azidobenzenesulfonamide is a specialized aromatic sulfonamide derivative featuring a reactive azide functional group. This unique bifunctional structure makes it a valuable photoaffinity labeling agent and a versatile chemical building block for synthesizing more complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, probe development, and polymer chemistry.

Application

• Photoaffinity Labeling (PAL): A critical reagent in chemical biology and proteomics for covalently capturing and identifying transient protein-ligand interactions upon UV light activation.
• Click Chemistry Intermediate: Serves as a precursor for synthesizing triazole-linked compounds via copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Pharmaceutical Research: Used in the design and synthesis of novel drug candidates, particularly as a sulfonamide-based pharmacophore with potential biological activity.
• Polymer Modification: Employed to introduce azide functionalities into polymers or surfaces for subsequent functionalization, creating advanced materials.
• Bioconjugation: Facilitates the attachment of reporter molecules, tags, or other functional groups to biomolecules for diagnostic or therapeutic purposes.
• Agrochemical Development: Acts as a key synthetic intermediate in creating new active ingredients for crop protection products.

Basic Information

Item	Detail
Product Name	4-Azidobenzenesulfonamide
CAS No.	36326-86-0
Molecular Formula	C6H6N4O2S
Molecular Weight	198.20 g/mol
Synonyms	p-Azidobenzenesulfonamide; 4-Azidobenzene-1-sulfonamide; Benzenesulfonamide, 4-azido-; Azidobenzene sulfonamide; NSC 401005; 4-Azido-benzenesulfonic acid amide
EINECS	Contact for details

Quality Control

Our 4-Azidobenzenesulfonamide is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR) for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and potentially shock-sensitive azide group, handle with appropriate precautions and avoid exposure to heat, strong acids, and heavy metals.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.