Description

19-Norpregn-4-En-20-Yn-17-Ol, Acetate, (17Alpha)- is a high-purity synthetic steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents, particularly in the fields of endocrinology and oncology.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of advanced steroid APIs and progestogens.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Process Chemistry: Employed in scaling up synthetic routes for pilot and commercial-scale manufacturing of steroid drugs.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies involving steroid receptors.

Basic Information

Product Name	19-Norpregn-4-En-20-Yn-17-Ol, Acetate, (17Alpha)-
CAS No.	36083-55-3
Molecular Formula	C23H32O2
Molecular Weight	340.50 g/mol
Synonyms	(17α)-17-Hydroxy-19-norpregn-4-en-20-yn-3-one acetate; 17α-Ethynyl-19-nortestosterone acetate; 19-Nor-17α-pregn-4-en-20-yn-17-ol acetate; Norethisterone acetate related compound; 17α-Ethynyl-19-norandrost-4-en-17β-ol-3-one acetate; 19-Norpregn-4-ene-20-yne-3,17-diol, 17-acetate, (17α)-; Lynestrenol acetate intermediate
EINECS	Contact for details

Quality Control

Our 19-Norpregn-4-En-20-Yn-17-Ol, Acetate, (17Alpha)- is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.