Description

5-Ethyl-5-(2-Methylbutyl)Barbituric Acid is a specialized barbiturate derivative, a class of compounds historically significant in medicinal chemistry. This high-purity intermediate is crucial for pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents and reference standards. It serves the needs of advanced R&D laboratories, fine chemical manufacturers, and academic institutions focused on neuropharmacology and synthetic organic chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of barbiturate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in regulatory testing.
• Biochemical Research: Employed in neuroscience and pharmacology studies to investigate GABAA receptor modulation and related neurological pathways.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex, functionally modified barbiturate analogs for structure-activity relationship (SAR) studies.
• Academic & Industrial R&D: Essential reagent for universities and corporate R&D centers exploring central nervous system (CNS) drug discovery and medicinal chemistry.

Basic Information

Product Name	5-Ethyl-5-(2-Methylbutyl)Barbituric Acid
CAS No.	36082-56-1
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	5-Ethyl-5-(2-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-Ethyl-5-(2-methylbutyl)barbituric acid; 5-(2-Methylbutyl)-5-ethylbarbituric acid; Barbituric acid, 5-ethyl-5-(2-methylbutyl)-; 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(2-methylbutyl)-; Butalbital Related Compound A (USP); 5-Allyl-5-isobutylbarbituric acid isomer
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(2-Methylbutyl)Barbituric Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.