Description

Butanoic Acid, 2-Bromo-3-Oxo-, 1,1-Dimethylethyl Ester is a specialized brominated keto ester building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive bromine atom and a ketone functionality, makes it a versatile precursor for constructing complex molecules. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce specific molecular fragments and create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing bromo-keto ester motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactive sites allow for the creation of compounds with specific modes of action.
• Organic Chemical Research: A valuable reagent in academic and industrial R&D labs for methodology development, including studies on cross-coupling reactions, nucleophilic substitutions, and cyclization processes.
• Fine Chemical Production: Employed in the multi-step synthesis of complex fine chemicals, flavors, and fragrances that require precise bromine incorporation.
• Material Science Precursor: Potential use in synthesizing specialized monomers or ligands for advanced polymeric or coordination complex materials.

Basic Information

Product Name	Butanoic Acid, 2-Bromo-3-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	36082-04-9
Molecular Formula	C9H15BrO3
Molecular Weight	251.12 g/mol
Synonyms	tert-Butyl 2-bromo-3-oxobutanoate; 2-Bromo-3-oxobutanoic acid tert-butyl ester; 3-Oxo-2-bromobutanoic acid 1,1-dimethylethyl ester; tert-Butyl 2-bromoacetoacetate; 2-Bromoacetoacetic acid tert-butyl ester; Butanoic acid, 2-bromo-3-oxo-, 1,1-dimethylethyl ester; Bromo tert-butyl acetoacetate
EINECS	Contact for details

Quality Control

Our production of Butanoic Acid, 2-Bromo-3-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including chromatography and spectroscopy, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical customers and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.