Description

(-)-4,5-o-Cyclohexylidenequinic Acid Lactone is a high-purity, chiral organic compound that serves as a critical advanced intermediate in sophisticated organic synthesis. Its unique fused bicyclic structure, incorporating a quinic acid-derived lactone and a cyclohexylidene protecting group, makes it a valuable building block for the development of complex, stereochemically defined molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of novel active pharmaceutical ingredients (APIs) and specialized chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, especially in antiviral, anti-inflammatory, or neurological drug candidates.
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in the construction of complex, enantiomerically pure molecules for medicinal chemistry and material science.
• Fine Chemical Production: Serves as a specialized building block in the multi-step synthesis of high-value agrochemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable reference standard and starting material for methodological development in organic chemistry and catalysis studies.
• Chemical Biology Probes: Potential use in the design and synthesis of molecular probes for studying biological pathways and enzyme mechanisms.

Basic Information

Product Name	(-)-4,5-o-Cyclohexylidenequinic Acid Lactone
CAS No.	35949-53-2
Molecular Formula	C13H18O5
Molecular Weight	254.28 g/mol
Synonyms	(-)-4,5-O-Cyclohexylidenequinic Acid γ-Lactone; (1S,3R,4R,5R)-3,4-Dihydroxy-8,9-dioxatricyclo[5.2.1.01,5]decan-10-one; 4,5-O-Cyclohexylidene-L-quinic Acid Lactone; 4,5-Cyclohexylidenequinic Acid Lactone; Quinic Acid 4,5-Cyclohexylidene Lactone; (-)-4,5-Cyclohexylidenequinic Acid γ-Lactone
EINECS	Contact for details

Quality Control

Our (-)-4,5-o-Cyclohexylidenequinic Acid Lactone is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.