Description

Ethyl n-[N2-[3-[Bis(2-Chloroethyl)Amino]-3-Phenyl-L-Alanyl]-N5-[Imino(Nitroamino)Methyl]-L-Ornithyl]-L-Norvalinate Monohydrobromide is a complex, high-purity synthetic peptide derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or reference standard in the synthesis and study of novel therapeutic agents, particularly in oncology. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of targeted anti-cancer compounds and other specialized peptide-based therapeutics.
• Biochemical Research: Used as a reference standard or probe in studies investigating enzyme inhibition, receptor binding, and cellular signaling pathways relevant to disease mechanisms.
• Preclinical Development: Employed in the formulation and efficacy testing of new drug candidates during early-stage development phases.
• Process Chemistry: Utilized for method development, optimization, and scale-up studies in active pharmaceutical ingredient (API) manufacturing.
• Analytical Standard: Provides a high-purity benchmark for analytical method validation, including HPLC, LC-MS, and NMR, ensuring accurate quantification and identification.

Basic Information

Item	Details
Product Name	Ethyl n-[N2-[3-[Bis(2-Chloroethyl)Amino]-3-Phenyl-L-Alanyl]-N5-[Imino(Nitroamino)Methyl]-L-Ornithyl]-L-Norvalinate Monohydrobromide
CAS No.	35849-53-7
Molecular Formula	C31H51BrCl2N8O6
Molecular Weight	750.60 g/mol
Synonyms	Ethyl N-[N2-[3-[bis(2-chloroethyl)amino]-3-phenyl-L-alanyl]-N5-[(nitroamino)iminomethyl]-L-ornithyl]-L-norvalinate hydrobromide; L-Norvaline, N-[N2-[3-[bis(2-chloroethyl)amino]-3-phenyl-L-alanyl]-N5-[(nitroamino)iminomethyl]-L-ornithyl]-, ethyl ester, monohydrobromide; Ethyl Norvalinate Derivative HBr Salt; Peptide Nitroamino Mustard Derivative; 35849-53-7
EINECS	Contact for details

Quality Control

Our Ethyl n-[N2-[3-[Bis(2-Chloroethyl)Amino]-3-Phenyl-L-Alanyl]-N5-[Imino(Nitroamino)Methyl]-L-Ornithyl]-L-Norvalinate Monohydrobromide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research-grade materials. Comprehensive Certificates of Analysis (COA) detailing purity (by HPLC), residual solvents, and other critical parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and should be handled and stored separately from strong oxidizers. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.