Description

n-Formyl-4-[Bis(2-Chloroethyl)Amino]-L-Phenylalanine is a specialized, high-purity chemical intermediate of significant importance in advanced pharmaceutical synthesis. This compound matters as a key precursor in the development of targeted therapeutic agents, particularly in oncology research. Pharmaceutical manufacturers and advanced research institutions need this material for the synthesis of complex molecules, including peptide-based drugs and alkylating agent conjugates.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of specialized chemotherapeutic agents and targeted cancer therapies.
• Oncology Research: Used in academic and industrial R&D for developing novel alkylating prodrugs and investigating new mechanisms of action.
• Peptide Conjugate Synthesis: Serves as a modified amino acid derivative for constructing peptide-drug conjugates (PDCs) with enhanced targeting properties.
• Bioconjugation Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other biopharmaceuticals requiring precise chemical linkage.
• Process Chemistry Development: Utilized in scaling up and optimizing synthetic routes for complex active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Acts as a research chemical for studying DNA alkylation and cellular response mechanisms in biological assays.

Basic Information

Product Name	n-Formyl-4-[Bis(2-Chloroethyl)Amino]-L-Phenylalanine
CAS No.	35849-41-3
Molecular Formula	C14H18Cl2N2O3
Molecular Weight	333.21 g/mol
Synonyms	N-Formylmelphalan; L-Phenylalanine, N-formyl-4-[bis(2-chloroethyl)amino]-; 4-[Bis(2-chloroethyl)amino]-L-phenylalanine N-formyl derivative; Formylmelphalan; N-Formyl-4-[bis(2-chloroethyl)amino]phenylalanine; N-For-Melphalan; NSC 330500; L-Phenylalanine, 4-[bis(2-chloroethyl)amino]-, N-formyl-
EINECS	Contact for details

Quality Control

Our n-Formyl-4-[Bis(2-Chloroethyl)Amino]-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific customer or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.