Description

N,n-Bis(2-Chloroethyl)Amidophosphoric Acid Disodium Salt is a specialized organophosphorus compound with a unique chemical structure that makes it a valuable intermediate in advanced synthesis. Its primary commercial value lies in its role as a key precursor for the development of targeted pharmaceutical agents and specialized agrochemicals. This product is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in creating novel therapeutic compounds, particularly in oncology and other specialized fields.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nitrogen mustard-based chemotherapeutic agents and other targeted drug molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its phosphoramidate structure for biological activity.
• Chemical Synthesis: Serves as a versatile reagent for introducing the bis(2-chloroethyl)amino group into more complex molecular architectures.
• Bioconjugation & Prodrug Development: Employed in research for creating targeted drug delivery systems and enzyme-activated prodrugs.
• Academic & Industrial R&D: A valuable compound for universities and corporate R&D centers exploring new organophosphorus chemistry and its applications.
• Material Science: Investigated as a monomer or cross-linking agent for creating specialized polymers with unique properties.

Basic Information

Product Name	N,n-Bis(2-Chloroethyl)Amidophosphoric Acid Disodium Salt
CAS No.	35763-11-2
Molecular Formula	C4H8Cl2NNa2O3P
Molecular Weight	282.87 g/mol
Synonyms	Phosphorodiamidic Acid, N,N-Bis(2-chloroethyl)-, Disodium Salt; Disodium N,N-Bis(2-chloroethyl)phosphorodiamidate; Nor-Nitrogen Mustard Phosphorodiamidate Disodium Salt; NSC 178248; 2-Chloro-N-(2-chloroethyl)-N-(phosphonatooxy)ethanaminium; Cyclophosphamide Impurity; Bis(2-chloroethyl)phosphorodiamidic Acid Disodium Salt
EINECS	Contact for details

Quality Control

Our N,n-Bis(2-Chloroethyl)Amidophosphoric Acid Disodium Salt is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and synthesis. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically assessed via HPLC, NMR, and titration methods. Specifications can be tailored to meet the stringent requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using an inert atmosphere to minimize the risk of oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.