Description

(S)-Piperidine-2-Carboxylic Acid Methyl Ester is a high-purity chiral building block and intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for the preparation of pharmaceutical compounds, particularly those containing the piperidine scaffold. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of various active pharmaceutical ingredients (APIs), including potential candidates for neurological and cardiovascular therapies.
• Asymmetric Synthesis: Used as a starting material or auxiliary in asymmetric catalytic reactions to construct complex, stereochemically defined molecules.
• Peptidomimetics & Drug Discovery: Serves as a constrained amino acid analog in the design and development of novel peptidomimetics and small molecule drug candidates.
• Agrochemical Synthesis: Employed in the research and production of advanced, enantiomerically pure agrochemicals and plant protection agents.
• Catalyst & Ligand Preparation: Utilized in the synthesis of chiral catalysts and ligands for use in homogeneous catalysis and other specialized chemical processes.
• Academic & Industrial R&D: A valuable reagent for methodological development and exploratory chemistry in both academic laboratories and corporate R&D facilities.

Basic Information

Product Name	(S)-Piperidine-2-Carboxylic Acid Methyl Ester
CAS No.	35677-83-9
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(S)-Methyl Pipecolate; (S)-Methyl Pipecolinate; (S)-Pipecolinic Acid Methyl Ester; (S)-Methyl 2-Piperidinecarboxylate; L-Pipecolinic Acid Methyl Ester; Methyl (S)-Pipecolate; (2S)-2-Piperidinecarboxylic Acid Methyl Ester; (S)-2-Methoxycarbonylpiperidine
EINECS	Contact for details

Quality Control

Our (S)-Piperidine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.