Description

tert-Butyl (4-Nitrobenzoyl)Oxycarbamate is a specialized chemical intermediate used in advanced organic synthesis. This compound is valued for its role as a protected carbamate derivative, facilitating the controlled introduction of functional groups in complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring nitroaromatic or protected amine functionalities.
• Agrochemical Research: Used in the development and scale-up of novel herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a reagent for the temporary protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Material Science: Intermediate in the production of specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	tert-Butyl (4-Nitrobenzoyl)Oxycarbamate
CAS No.	35657-41-1
Molecular Formula	C12H14N2O6
Molecular Weight	282.25 g/mol
Synonyms	tert-Butyl N-[(4-Nitrobenzoyl)oxy]carbamate; Carbamic acid, N-[(4-nitrobenzoyl)oxy]-, 1,1-dimethylethyl ester; BOC-ONB; (tert-Butoxycarbonyloxy)(4-nitrobenzoyl)amine; 4-Nitrobenzoic acid, (tert-butoxycarbonyl) ester; tert-Butyloxycarbonyl 4-nitrobenzoate; O-(4-Nitrobenzoyl)-N-(tert-butoxycarbonyl)hydroxylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Nitrobenzoyl)Oxycarbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.