Description

[(tert-Butoxy)Carbonyl]Amino 2,2-Dimethylpropanoate is a specialized Boc-protected amino acid derivative, serving as a crucial building block in advanced organic synthesis. Its primary value lies in providing a sterically hindered, acid-labile protecting group for amines, enabling selective reactions in complex multi-step sequences. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly in the development of novel peptides, active pharmaceutical ingredients (APIs), and other fine chemicals.

Application

• Pharmaceutical Intermediates: A key synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Protecting Group Chemistry: The tert-butoxycarbonyl (Boc) group is selectively introduced to protect amine functionalities during complex organic transformations.
• Bioconjugation & Linker Chemistry: Employed in the design and synthesis of chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugates.
• Agrochemical Research: Serves as a building block in the research and development of novel crop protection agents and pesticides.
• Material Science: Used in the synthesis of specialized monomers for advanced polymers and functional materials.

Basic Information

Item	Details
Product Name	[(tert-Butoxy)Carbonyl]Amino 2,2-Dimethylpropanoate
CAS No.	35657-40-0
Molecular Formula	C11H21NO4
Molecular Weight	231.29 g/mol
Synonyms	Boc-Amino Pivalate; N-(tert-Butoxycarbonyl)-2,2-dimethylglycine; N-Boc-2-aminoisobutyric Acid; 2-[(tert-Butoxycarbonyl)amino]-2-methylpropanoic Acid; N-Boc-Amino Isobutyric Acid; N-Boc-2-Aminoisobutyric Acid; BOC-AIB-OH; 2-Methyl-N-[(2-methyl-2-propanyl)oxycarbonyl]alanine
EINECS	Contact for details

Quality Control

Our [(tert-Butoxy)Carbonyl]Amino 2,2-Dimethylpropanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.