Description

1,4-Dioxaspiro[4.4]Nonane-6-Propiononitrile CAS NO 35579-33-0 is a high-purity, versatile spirocyclic nitrile building block used in advanced organic synthesis. This compound is valued for its rigid, three-dimensional structure, which is crucial for constructing complex molecular architectures in pharmaceutical and agrochemical research. It serves as a key intermediate for medicinal chemists and process development scientists working on novel active ingredients, particularly in the areas of central nervous system (CNS) agents and crop protection chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its spirocyclic scaffold.
• Material Science Research: Serves as a precursor for specialty polymers and advanced organic materials requiring specific steric and electronic properties.
• Chemical Biology Probes: Utilized in the development of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Catalyst Ligand Development: Acts as a starting material for synthesizing novel chiral ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-6-Propiononitrile
CAS No.	35579-33-0
Molecular Formula	C11H15NO2
Molecular Weight	193.24 g/mol
Synonyms	6-(2-Cyanoethyl)-1,4-dioxaspiro[4.4]nonane; 1,4-Dioxaspiro[4.4]nonane-6-propionitrile; Spiro[1,3-dioxolane-2,1'-cyclopentane]-4-acetonitrile, 5',6'-dihydro-; 2-(1,4-Dioxaspiro[4.4]non-6-yl)acetonitrile; 6-(Cyanomethyl)-1,4-dioxaspiro[4.4]nonane
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.4]Nonane-6-Propiononitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.