Description

2,6-Bis-(Trimethylsilyl)Pyridine is a versatile organosilicon compound that serves as a valuable protecting group reagent and a key intermediate in advanced organic synthesis. Its primary value lies in its ability to act as a sterically hindered, non-nucleophilic base and a silylating agent, facilitating complex transformations under mild conditions. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• As a protecting group reagent for alcohols and amines in multi-step organic synthesis.
• As a key silylating agent and non-nucleophilic base in the preparation of sensitive organometallic compounds.
• As a crucial intermediate in pharmaceutical synthesis for the development of novel drug candidates and active pharmaceutical ingredients (APIs).
• In agrochemical research for the synthesis of advanced pesticides and herbicides.
• In material science for the surface modification of silicon-based materials and the synthesis of specialty polymers.
• For catalyst ligand synthesis in asymmetric catalysis and cross-coupling reactions.

Basic Information

Product Name	2,6-Bis-(Trimethylsilyl)Pyridine
CAS No.	35505-52-3
Molecular Formula	C11H21NSi2
Molecular Weight	223.47 g/mol
Synonyms	2,6-Bis(trimethylsilyl)pyridine; 2,6-Di(trimethylsilyl)pyridine; Pyridine, 2,6-bis(trimethylsilyl)-; 2,6-BTSP; 2,6-Bis-TMS-pyridine; 2,6-Bis(trimethylsilyl)azine; DTSP
EINECS	Contact for details

Quality Control

Our 2,6-Bis-(Trimethylsilyl)Pyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including GC, HPLC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.