Description

Rel-Methyl (1R,2R)-2-(Hydroxymethyl)Cyclopropane-1-Carboxylate is a high-purity, enantiomerically pure cyclopropane derivative that serves as a critical chiral building block in advanced organic synthesis. Its value lies in providing a rigid, stereodefined scaffold essential for constructing complex molecules with precise three-dimensional architecture. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of antiviral, anticancer, and central nervous system (CNS) active drug candidates.
• Agrochemical Research: Used in creating novel, stereospecific pesticides and herbicides with enhanced efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Incorporated into specialty polymers and advanced materials to impart specific stereochemical and physical properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Process Chemistry: Employed in methodological development and scale-up studies for complex synthetic routes.

Basic Information

Product Name	Rel-Methyl (1R,2R)-2-(Hydroxymethyl)Cyclopropane-1-Carboxylate
CAS No.	35501-83-8
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(1R,2R)-Methyl 2-(Hydroxymethyl)cyclopropanecarboxylate; (1R,2R)-Methyl 2-(Hydroxymethyl)cyclopropane-1-carboxylate; Methyl (1R,2R)-2-(Hydroxymethyl)cyclopropanecarboxylate; Rel-(1R,2R)-Methyl 2-(Hydroxymethyl)cyclopropanecarboxylate; (1R-cis)-Methyl 2-(Hydroxymethyl)cyclopropanecarboxylate; cis-Methyl 2-(Hydroxymethyl)cyclopropanecarboxylate; Chiral Cyclopropane Ester
EINECS	Contact for details

Quality Control

Our Rel-Methyl (1R,2R)-2-(Hydroxymethyl)Cyclopropane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.