Description

Methyl 2,5-Bis(2,2,2-Trifluoroethoxy)Benzoate is a high-purity fluorinated aromatic ester, serving as a critical advanced intermediate in the synthesis of complex organic molecules. Its value lies in the unique combination of the benzoate ester moiety with trifluoroethoxy side chains, which can impart desirable properties like enhanced lipophilicity and metabolic stability to final compounds. This specialty chemical is primarily needed by research and development laboratories, pharmaceutical companies, and agrochemical manufacturers focused on creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated motifs for improved bioavailability and patent life.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and insecticides where the trifluoroethoxy groups contribute to biological activity and environmental persistence profiles.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, where such modifications can fine-tune dielectric anisotropy and thermal stability.
• Polymer & Specialty Chemical Modifier: Incorporated into polymer chains or used to synthesize specialty monomers to create materials with specific surface energies, chemical resistance, or optical properties.
• Organic Synthesis & Catalysis Research: Employed in academic and industrial R&D for methodological studies in cross-coupling reactions and as a ligand precursor in catalyst design.

Basic Information

Product Name	Methyl 2,5-Bis(2,2,2-Trifluoroethoxy)Benzoate
CAS No.	35480-31-0
Molecular Formula	C12H10F6O4
Molecular Weight	332.20 g/mol
Synonyms	Benzoic acid, 2,5-bis(2,2,2-trifluoroethoxy)-, methyl ester; Methyl 2,5-di(2,2,2-trifluoroethoxy)benzoate; 2,5-Bis(2,2,2-trifluoroethoxy)benzoic acid methyl ester; Methyl 2,5-bis(trifluoroethoxy)benzoate; 35480-31-0; Methyl 2,5-di(trifluoroethoxy)benzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,5-Bis(2,2,2-Trifluoroethoxy)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. Handle and store in accordance with good laboratory and chemical hygiene practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.