Description

[4-(2-Isothiocyanatoethyl)-1,2-Phenylene]Bis(Oxy)Bis(Trimethylsilane) is a specialized organosilicon reagent featuring a reactive isothiocyanate group. This compound is valued for its role as a versatile silylating agent and bifunctional linker in advanced synthetic chemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science sectors for the synthesis of complex molecules and functionalized surfaces.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing silyl-protected phenolic groups or creating thiourea linkages.
• Agrochemical Synthesis: Serves as a key building block for novel herbicides, fungicides, and plant growth regulators requiring specific silicon-containing motifs.
• Surface Modification Agent: Functionalizes silica, glass, or metal oxide surfaces to create specific reactive sites for chromatography, sensors, or catalysis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty silicones and hybrid organic-inorganic polymers.
• Bioconjugation Reagent: Facilitates the labeling and immobilization of biomolecules (e.g., proteins, peptides) for diagnostic assays and research applications.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	[4-(2-Isothiocyanatoethyl)-1,2-Phenylene]Bis(Oxy)Bis(Trimethylsilane)
CAS No.	35424-97-6
Molecular Formula	C16H27NO2SSi2
Molecular Weight	353.62 g/mol
Synonyms	1,2-Bis(trimethylsilyloxy)-4-(2-isothiocyanatoethyl)benzene; 4-(2-Isothiocyanatoethyl)benzene-1,2-diyl bis(trimethylsilyl) ether; 4-(2-Isothiocyanatoethyl)pyrocatechol bis(trimethylsilyl) ether; 2-(3,4-Bis(trimethylsilyloxy)phenyl)ethyl isothiocyanate; BTSI Reagent (common abbreviation); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of [4-(2-Isothiocyanatoethyl)-1,2-Phenylene]Bis(Oxy)Bis(Trimethylsilane) adheres to strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.