Description

Tetrahydro-η,4-Bis[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]-2-Furanoctanoic Acid Methyl Ester is a sophisticated organosilicon-protected synthetic intermediate of significant value in advanced organic synthesis. Its primary commercial importance lies in its role as a key protected precursor for the construction of complex natural product analogs and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly those working on prostaglandin-related compounds and other lipid mediators.

Application

• Pharmaceutical Intermediate: Critical building block in the multi-step synthesis of prostaglandin analogs and other bioactive lipid molecules.
• Fine Chemical Synthesis: Used as a protected synthon in the preparation of complex, high-value specialty chemicals for research and development.
• Academic & Industrial R&D: Serves as a valuable reagent in methodological development and the synthesis of novel chemical entities for biological screening.
• Prostanoid Research: Specifically utilized in the synthesis of tetrahydrofuran-containing intermediates relevant to prostanoid chemistry.
• Process Chemistry: Employed in route scouting and scale-up studies for the production of target active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Tetrahydro-η,4-Bis[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]-2-Furanoctanoic Acid Methyl Ester
CAS No.	35275-56-0
Molecular Formula	C30H58O6Si3
Molecular Weight	599.04 g/mol
Synonyms	Methyl 5-[3-[(Trimethylsilyl)oxy]-1-octen-1-yl]-4,7-bis(trimethylsilyloxy)-2-oxabicyclo[3.3.0]octane-3-carboxylate; Methyl 5-[3-[(Trimethylsilyl)oxy]-1-octenyl]-4,7-bis[(trimethylsilyl)oxy]-2-oxabicyclo[3.3.0]octane-3-carboxylate; Corey Lactone Diol Bis-TMS Ether Methyl Ester; 11-Deoxy-PGE1 Methyl Ester Bis(trimethylsilyl) Ether; Prostaglandin Intermediate; Tetrahydrofuran Prostanoid Intermediate
EINECS	Contact for details

Quality Control

Every batch of this high-purity synthetic intermediate is produced and tested under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for critical R&D and scale-up work. Our quality systems are designed to support cGMP compliance for pharmaceutical applications, with documentation available to meet rigorous audit requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Keep away from oxidizing agents and moisture. For long-term storage, consider refrigeration at 2-8°C under inert conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.