Description

8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Trimethylsilyl Ester is a high-purity, multi-functional silyl-protected intermediate of significant importance in advanced organic synthesis. Its primary value lies in providing a stable, reactive platform for constructing complex molecular architectures, particularly in the synthesis of prostaglandins and other bioactive lipid mediators. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require precise and reliable building blocks for complex multi-step syntheses.

Application

• Key Intermediate in Prostaglandin Synthesis: Serves as a critical protected precursor in the total synthesis of prostaglandin analogs and related eicosanoids.
• Advanced Pharmaceutical Intermediates (APIs): Used in the research and development of novel therapeutic agents targeting inflammation, cardiovascular function, and other physiological pathways.
• Fine Chemical Synthesis: Employed as a versatile building block for constructing complex, polyfunctional molecules in academic and industrial research settings.
• Agrochemical Research: Utilized in the development of new active ingredients that mimic or interfere with natural plant signaling molecules.
• Methodology Development: Acts as a model substrate for developing new synthetic methodologies involving silyl protecting group chemistry and stereoselective transformations.

Basic Information

Product Name	8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Trimethylsilyl Ester
CAS No.	35275-55-9
Molecular Formula	C33H62O6Si3
Molecular Weight	651.12 g/mol
Synonyms	5-Octenoic acid, 8-[tetrahydro-4-[(trimethylsilyl)oxy]-5-[3-[(trimethylsilyl)oxy]-1-octen-1-yl]-2-furanyl]-8-[(trimethylsilyl)oxy]-, trimethylsilyl ester; Trimethylsilyl 8-[tetrahydro-4-(trimethylsilyloxy)-5-[3-(trimethylsilyloxy)-1-octenyl]-2-furyl]-8-(trimethylsilyloxy)-5-octenoate; Prostaglandin F2α TMS ester intermediate; Corey Lactone TMS derivative; Silyl-protected prostaglandin intermediate
EINECS	Contact for details

Quality Control

Our 8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider storing under inert gas in a freezer (-20°C).

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.