Description

8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Methyl Ester is a high-purity, protected synthetic intermediate of significant value in advanced organic synthesis. Its complex structure, featuring multiple trimethylsilyl (TMS) protecting groups, makes it a critical precursor for constructing intricate natural product analogs and bioactive molecules. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for projects involving prostaglandin synthesis and other complex lipid-based therapeutics.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of prostaglandins and related eicosanoids, which are vital for drug discovery in inflammation, cardiovascular, and reproductive health.
• Advanced Organic Synthesis: Serves as a sophisticated building block for constructing complex, chiral molecular architectures in academic and industrial R&D settings.
• Fine Chemical Production: Used in the manufacture of high-value specialty chemicals where precise stereochemistry and functional group protection are required.
• Biochemical Research: Employed as a tool compound to study lipid signaling pathways and enzyme mechanisms in biological systems.
• Process Chemistry Development: Utilized for scaling up synthetic routes to complex target molecules, benefiting from its stability as a protected intermediate.

Basic Information

Product Name	8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Methyl Ester
CAS No.	35275-54-8
Molecular Formula	C30H56O6Si2
Molecular Weight	569.0 g/mol (approx.)
Synonyms	Methyl 8-[(Trimethylsilyl)oxy]-8-[tetrahydro-4-[(trimethylsilyl)oxy]-5-[3-[(trimethylsilyl)oxy]-1-octen-1-yl]-2-furyl]-5-octenoate; Prostaglandin F2α TMS Ester Intermediate; 8-[Tetrahydro-4-[(trimethylsilyl)oxy]-5-[3-[(trimethylsilyl)oxy]-1-octenyl]-2-furanyl]-8-[(trimethylsilyl)oxy]-5-octenoic acid methyl ester; PGF2α Trimethylsilyl Ester Derivative; Protected Prostaglandin Intermediate; TMS-protected PGF2α methyl ester.
EINECS	Contact for details

Quality Control

Our 8-[Tetrahydro-4-[(Trimethylsilyl)Oxy]-5-[3-[(Trimethylsilyl)Oxy]-1-Octenyl]Furan-2-Yl]-8-[(Trimethylsilyl)Oxy]-5-Octenoic Acid Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.