Description

Ethyl 6-Iodo-4-Oxo-4H-Chromene-2-Carboxylate is a high-purity, functionalized chromene derivative, serving as a critical synthetic intermediate for advanced organic chemistry. Its value lies in the strategic placement of iodine and ester functional groups, which enable versatile downstream modifications, including cross-coupling reactions and heterocyclic ring formation. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, as well as for fine chemical synthesis requiring precise molecular scaffolds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the chromene core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials and fluorescent dyes due to its conjugated chromene structure.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis, including palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Fine Chemical Synthesis: Intermediate for creating complex natural product analogs and specialty chemicals.

Basic Information

Product Name	Ethyl 6-Iodo-4-Oxo-4H-Chromene-2-Carboxylate
CAS No.	35204-44-5
Molecular Formula	C₁₂H₉IO₄
Molecular Weight	344.10 g/mol
Synonyms	6-Iodo-4-oxo-4H-chromene-2-carboxylic acid ethyl ester; Ethyl 6-iodo-4-oxochromene-2-carboxylate; 2-Carbethoxy-6-iodo-4-chromone; 6-Iodo-4-chromone-2-carboxylic acid ethyl ester; 6-Iodo-2-ethoxycarbonyl-4H-chromen-4-one; 35204-44-5; Chromone derivative, 6-iodo-
EINECS	Contact for details

Quality Control

Every batch of Ethyl 6-Iodo-4-Oxo-4H-Chromene-2-Carboxylate is produced and tested under strict quality management protocols to ensure consistency and reliability for your research and production needs. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.