Description

(3S,6S)-4β-Acetoxy-3,3Aβ,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-3β,9-Dimethylspiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One is a high-purity, complex spirocyclic organic compound with a defined stereochemistry, serving as a critical advanced intermediate in sophisticated organic synthesis. Its intricate fused-ring structure containing azulene, furan, and oxirane moieties makes it a valuable building block for the development of novel pharmacologically active molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for complex target molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its unique polycyclic framework.
• Process Chemistry: Serves as a defined starting material or intermediate in the scalable synthesis of active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Exploited for its fixed stereocenters in the construction of other enantiomerically pure compounds.
• Chemical Biology Probes: Potential use in the development of molecular probes for studying biological pathways and target engagement.
• Academic Research: Employed in universities and research institutes for methodological studies in organic synthesis and natural product analog synthesis.

Basic Information

Product Name	(3S,6S)-4β-Acetoxy-3,3Aβ,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-3β,9-Dimethylspiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One
CAS No.	35144-09-3
Molecular Formula	C19H24O5
Molecular Weight	332.39 g/mol
Synonyms	4β-Acetoxy-3β,9-dimethyldecahydrospiro[azuleno[4,5-b]furan-6,2'-oxiran]-2-one; Spiro[azuleno[4,5-b]furan-6(2H),2'-oxiran]-2-one, 4-(acetyloxy)-3,3a,4,5,6,6a,7,9,9a,9b-decahydro-3,9-dimethyl-, (3S,3aS,4S,6R,6aS,9R,9aS,9bS)-; (3S,3aS,4S,6R,6aS,9R,9aS,9bS)-4-(Acetyloxy)-3,9-dimethyldecahydrospiro[azuleno[4,5-b]furan-6,2'-oxiran]-2-one; A related stereoisomer or derivative of Guaiazulene. Contact for specific isomer details.
EINECS	Contact for details

Quality Control

Every batch of (3S,6S)-4β-Acetoxy-3,3Aβ,4,5,6Aβ,7,9Aβ,9Bα-Octahydro-3β,9-Dimethylspiro[Azuleno[4,5-B]Furan-6(2H),2'-Oxiran]-2-One is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert gas atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.