Description

tert-Butyl 2-Bromo-2-Phenylacetate is a versatile and high-purity organic building block, specifically an α-bromo ester derivative. This compound is valued for its role as a key synthetic intermediate in the preparation of complex molecules, particularly through coupling and alkylation reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for process development and scale-up.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing phenylacetic acid derivatives.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Organic Synthesis Building Block: Serves as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and in nucleophilic substitution reactions to introduce the 2-phenylacetate moiety.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D laboratories exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	tert-Butyl 2-Bromo-2-Phenylacetate
CAS No.	35132-16-2
Molecular Formula	C12H15BrO2
Molecular Weight	271.15 g/mol
Synonyms	2-Bromo-2-phenylacetic acid tert-butyl ester; tert-Butyl α-bromophenylacetate; α-Bromophenylacetic acid tert-butyl ester; Phenylacetic acid, 2-bromo-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl 2-bromo-2-phenylacetate; (2-Bromo-2-phenyl)acetic acid tert-butyl ester; Bromophenylacetic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Bromo-2-Phenylacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.