Description

Triethyl 2-Phosphonopentanoate is a high-purity organophosphorus compound, specifically a phosphonate ester, widely utilized as a critical building block in organic synthesis. Its primary value lies in its role as a versatile Horner-Wadsworth-Emmons (HWE) reagent, enabling the efficient formation of carbon-carbon double bonds to synthesize complex molecules. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise and scalable methods for olefination reactions.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing α,β-unsaturated carbonyl systems and other complex olefins.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific alkene functionalities.
• Material Science Precursors: Serves as a monomer or intermediate in the development of specialized polymers, coatings, and functional materials.
• Fine Chemical Manufacturing: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic & Industrial R&D: A fundamental tool in research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name	Triethyl 2-Phosphonopentanoate
CAS No.	35051-49-1
Molecular Formula	C11H23O5P
Molecular Weight	266.27 g/mol
Synonyms	Triethyl 2-phosphonovalerate; Diethyl (3-ethoxy-3-oxopropyl)phosphonate; (Triethoxyphosphinyl)pentanoic acid, ethyl ester; 2-(Diethoxyphosphoryl)pentanoic acid ethyl ester; Ethyl 2-(diethoxyphosphoryl)pentanoate; Phosphonopentanoic acid, triethyl ester; HWE Reagent for pentanoate; Valeric acid, 2-phosphono-, triethyl ester
EINECS	Contact for details

Quality Control

Our Triethyl 2-Phosphonopentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR), to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve optimal reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.430 - 1.440
Density (g/mL, 20°C)	1.05 - 1.15

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.