Description

4-(Trifluoromethoxy)Phenyl Isocyanate is a specialized aromatic isocyanate monomer featuring a trifluoromethoxy substituent, which imparts unique chemical and physical properties. This compound is a critical building block for synthesizing advanced materials with enhanced stability, hydrophobicity, and specific reactivity profiles. It is primarily required by R&D chemists and process engineers in the agrochemical, pharmaceutical, and specialty polymer industries for creating novel active ingredients, intermediates, and high-performance coatings.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, where the trifluoromethoxy group contributes to biological activity and environmental stability.
• Pharmaceutical Building Block: Used to create novel active pharmaceutical ingredients (APIs) and intermediates, particularly in drug discovery programs targeting metabolic and central nervous system diseases.
• Specialty Polymer Synthesis: Serves as a monomer for producing polyurethanes, polyureas, and other polymers with tailored properties such as chemical resistance, low surface energy, and thermal stability for advanced coatings and adhesives.
• Liquid Crystal & Electronic Materials: Employed in the development of advanced materials for electronic displays and optoelectronic applications due to its molecular structure and reactivity.
• Cross-linking Agent: Functions as an effective cross-linker for resins and polymers, enhancing mechanical strength and durability in composite materials.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating novel chemical entities.

Basic Information

Product Name	4-(Trifluoromethoxy)Phenyl Isocyanate
CAS No.	35037-73-1
Molecular Formula	C8H4F3NO2
Molecular Weight	203.12 g/mol
Synonyms	p-(Trifluoromethoxy)phenyl isocyanate; 1-Isocyanato-4-(trifluoromethoxy)benzene; 4-Trifluoromethoxyphenyl isocyanate; α,α,α-Trifluoro-p-cresyl isocyanate; Isocyanic acid 4-(trifluoromethoxy)phenyl ester; NSC 406916; 4-(Trifluoromethoxy)benzenisocyanate
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Phenyl Isocyanate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at temperatures between 2°C and 8°C (refrigerated) for long-term stability, as this compound is hygroscopic (moisture-sensitive). Allow the container to reach ambient temperature before opening to prevent moisture condensation. Keep away from heat, sparks, open flames, and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.4 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.