Description

2-O,3-O:5-O,6-o-Bis(1-Methylethylidene)-D-Mannononitrile 4-Benzoate is a high-purity, protected carbohydrate derivative, specifically a benzoylated mannononitrile diacetonide. This compound is a critical chiral intermediate and building block in sophisticated organic synthesis, valued for its defined stereochemistry and protective group strategy. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of nucleoside analogs, antiviral agents, and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Organic Synthesis Building Block: Used in glycosylation reactions and as a precursor for constructing complex sugar-modified compounds and natural product derivatives.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development and study of stereoselective chemical transformations.
• Carbohydrate Chemistry: Fundamental research tool for studying protected sugar chemistry, ring-opening reactions, and functional group manipulations.
• Chemical Biology Probes: Can be utilized to create labeled or modified sugars for investigating biological recognition and metabolic pathways.

Basic Information

Item	Detail
Product Name	2-O,3-O:5-O,6-o-Bis(1-Methylethylidene)-D-Mannononitrile 4-Benzoate
CAS No.	35023-81-5
Molecular Formula	C20H23NO6
Molecular Weight	373.40 g/mol
Synonyms	D-Mannononitrile, 4-benzoate, 2,3:5,6-bis-O-(1-methylethylidene)-; 2,3:5,6-Di-O-isopropylidene-D-mannononitrile 4-benzoate; 4-O-Benzoyl-2,3:5,6-di-O-isopropylidene-D-mannononitrile; Diacetone mannononitrile benzoate; Protected D-mannononitrile benzoate
EINECS	Contact for details

Quality Control

Our 2-O,3-O:5-O,6-o-Bis(1-Methylethylidene)-D-Mannononitrile 4-Benzoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and spectroscopic identification (NMR, IR, MS), to ensure it meets the exacting standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound should be handled in a moisture-controlled environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.