Description

Pyridine, 4-Chloro-2,6-Difluoro- is a halogenated pyridine derivative that serves as a versatile and valuable building block in advanced organic synthesis. This compound is prized for its unique reactivity profile, enabling the precise introduction of a difluoro-chloro substituted pyridine scaffold into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the pyridine core contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional organic materials, such as liquid crystals or electronic chemicals, due to its halogenated structure.
• Custom Synthesis and Contract Manufacturing: An essential starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	Pyridine, 4-Chloro-2,6-Difluoro-
CAS No.	34968-33-7
Molecular Formula	C5H2ClF2N
Molecular Weight	149.53 g/mol
Synonyms	4-Chloro-2,6-difluoropyridine; 2,6-Difluoro-4-chloropyridine; 4-Chloro-2,6-difluoro-pyridine; Pyridine, 4-chloro-2,6-difluoro-; 34968-33-7; 4-Chloro-2,6-difluoro pyridine
EINECS	Contact for details

Quality Control

Our Pyridine, 4-Chloro-2,6-Difluoro- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.