Description

L-(-)-Norepinephrine (+)-Bitartrate Salt Monohydrate is a high-purity, crystalline salt form of the essential neurotransmitter and hormone norepinephrine. This compound is critical for research and development in neuropharmacology and cardiovascular medicine, serving as a key reference standard and active pharmaceutical ingredient (API) intermediate. It is primarily utilized by pharmaceutical manufacturers, analytical laboratories, and academic research institutions engaged in the study of adrenergic receptors, stress responses, and drug discovery programs.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, GC-MS) and the qualification of assays in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key starting material or intermediate in the synthesis of advanced adrenergic drugs and diagnostic agents.
• Biochemical Research: Essential for in vitro and ex vivo studies investigating the mechanisms of norepinephrine reuptake, receptor binding affinity, and signal transduction pathways.
• Cardiovascular Research: Employed in experimental models to study vasoconstriction, blood pressure regulation, and cardiac output.
• Neuropharmacology Studies: Used to explore the role of norepinephrine in the central nervous system, including its effects on alertness, arousal, and stress.
• Cell Culture & Diagnostic Kits: A component in specialized cell culture media and as a calibrant in diagnostic test kits for catecholamine analysis.

Basic Information

Product Name	L-(-)-Norepinephrine (+)-Bitartrate Salt Monohydrate
CAS No.	34888-32-9
Molecular Formula	C12H19NO9 • H2O
Molecular Weight	337.29 g/mol (Monohydrate)
Synonyms	(-)-Norepinephrine D-bitartrate monohydrate; L-Noradrenaline (+)-bitartrate salt monohydrate; (R)-4-(2-Amino-1-hydroxyethyl)benzene-1,2-diol (2R,3R)-2,3-dihydroxysuccinate monohydrate; Levarterenol bitartrate monohydrate; Noradrenaline acid tartrate monohydrate; Arterenol bitartrate; L-(-)-Norepinephrine hydrogen tartrate monohydrate; (R)-Noradrenaline (+)-bitartrate
EINECS	Contact for details

Quality Control

Every batch of our L-(-)-Norepinephrine (+)-Bitartrate Salt Monohydrate is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC purity, chiral purity, and residual solvent data are available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. The material is hygroscopic and should be kept in a cool, dry place. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	4.5% - 6.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.