Description

L-Aspartic Acid 1-tert-Butyl 4-Methyl is a protected derivative of the essential amino acid L-aspartic acid, featuring tert-butyl and methyl ester protecting groups. This compound is a crucial chiral building block and intermediate in the synthesis of complex peptides, pharmaceuticals, and fine chemicals, offering precise stereochemical control. It is primarily needed by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for developing active pharmaceutical ingredients (APIs) and other high-value specialty molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of peptide-based drugs, enzyme inhibitors, and other therapeutic agents.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis (SPPS) where protected aspartic acid residues are required to prevent side reactions.
• Biochemical Research: Serves as a standard or reagent in metabolic pathway studies and proteomics research.
• Agrochemical Synthesis: An intermediate in the production of certain herbicides, pesticides, and plant growth regulators with specific chiral requirements.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that utilize aspartic acid derivatives.

Basic Information

Product Name	L-Aspartic Acid 1-tert-Butyl 4-Methyl
CAS No.	34582-30-4
Molecular Formula	C9H17NO4
Molecular Weight	203.24 g/mol
Synonyms	L-Aspartic acid β-tert-butyl α-methyl ester; (S)-2-(tert-Butoxycarbonylamino)succinic acid 4-methyl ester; Boc-Asp(OMe)-OH; Boc-L-aspartic acid 4-methyl ester; N-Boc-L-aspartic acid 4-methyl ester; 1-(tert-Butoxycarbonyl)-L-aspartic acid 4-methyl ester; N-(tert-Butoxycarbonyl)-L-aspartic acid β-methyl ester; Protected L-Aspartic Acid
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid 1-tert-Butyl 4-Methyl is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, correct stereochemistry, and consistency. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as assay, enantiomeric purity, and impurity profiles. We support compliance with cGMP, ICH guidelines, and other relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.