Description

[S,(+)]-2-o-Linoleoyl-1-o-Stearoyl-3-o-Trityl-L-Glycerol CAS NO 34487-25-7 is a high-purity, enantiomerically pure synthetic glyceride derivative, specifically designed as a critical intermediate in advanced organic synthesis and pharmaceutical research. This compound is valued for its defined stereochemistry and protected functional groups, which enable precise and controlled chemical transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of complex lipids, prodrugs, and chiral building blocks.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in lipid-based drug delivery systems.
• Lipid Chemistry Research: Used as a protected precursor in the study of glycerolipid metabolism, enzyme kinetics, and the synthesis of structurally defined phospholipids and triglycerides.
• Prodrug Synthesis: Serves as a versatile scaffold for designing and synthesizing prodrugs aimed at improving drug solubility, bioavailability, and targeted release.
• Chiral Auxiliary/Resolving Agent: Its stable, trityl-protected configuration makes it useful in asymmetric synthesis and as a tool for chiral separations.
• Biochemical Probe Development: Employed in creating labeled or modified lipids for tracing metabolic pathways and studying membrane biophysics.
• Agrochemical Synthesis: Acts as an intermediate in the production of specialized surfactants and adjuvants with specific stereochemical requirements.

Basic Information

Product Name	[S,(+)]-2-o-Linoleoyl-1-o-Stearoyl-3-o-Trityl-L-Glycerol
CAS No.	34487-25-7
Molecular Formula	C84H122O5
Molecular Weight	1211.88 g/mol
Synonyms	(S)-2-Linoleoyl-1-stearoyl-3-trityl-sn-glycerol; 1-Stearoyl-2-linoleoyl-3-trityl-sn-glycerol; sn-Glycerol 1-stearate 2-linoleate 3-trityl ether (S-isomer); L-Glycerol, 2-linoleoyl-1-stearoyl-3-trityl-, (S)-; Trityl-protected mixed-acid triglyceride; 3-O-Trityl-1-O-stearoyl-2-O-linoleoyl-sn-glycerol; Protected diglyceride derivative; CAS 34487-25-7
EINECS	Contact for details

Quality Control

Our [S,(+)]-2-o-Linoleoyl-1-o-Stearoyl-3-o-Trityl-L-Glycerol is manufactured under strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis to confirm identity, enantiomeric excess, and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We support compliance with cGMP guidelines for advanced intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, cool place. The product is light-sensitive (store away from light). For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) to prevent potential oxidation.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.