Description

Ethyl cis-3-Iodocrotonate, 97 is a high-purity, light-sensitive organic iodide ester, a versatile building block in advanced organic synthesis. This compound is valued for its role in facilitating key carbon-carbon bond-forming reactions, such as Heck coupling and other palladium-catalyzed cross-couplings, enabling the construction of complex molecular architectures. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring stereoselective introduction of functionalized olefins.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the iodocrotonate moiety acts as a reactive handle.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique optical or electronic properties.
• Cross-Coupling Reactions: An excellent substrate for Heck, Stille, and Suzuki-Miyaura cross-coupling reactions to form conjugated systems.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and catalysis studies.
• Fine Chemical Production: Employed in the multi-step synthesis of flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Ethyl cis-3-Iodocrotonate, 97
CAS No.	34450-62-9
Molecular Formula	C6H9IO2
Molecular Weight	240.04 g/mol
Synonyms	Ethyl (Z)-3-Iodobut-2-enoate; (Z)-Ethyl 3-Iodocrotonate; cis-Ethyl 3-Iodocrotonate; 3-Iodocrotonic Acid Ethyl Ester; Ethyl (Z)-3-Iodo-2-butenoate; 2-Butenoic acid, 3-iodo-, ethyl ester, (2Z)-; Ethyl 3-iodo-(Z)-2-butenoate
EINECS	Contact for details

Quality Control

Our Ethyl cis-3-Iodocrotonate, 97 is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to verify identity, purity, and isomeric composition. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, the container should be amber-colored or kept in secondary opaque packaging. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Isomeric Purity (cis-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.