Description

(-)-Nortrachelogenin CAS NO 34444-37-6 is a high-purity lignan compound known for its distinct biological activity and stereochemistry. This compound serves as a critical reference standard and a valuable building block in advanced pharmaceutical and biochemical research. It is primarily utilized by research institutions and pharmaceutical developers focused on natural product chemistry, drug discovery, and metabolic studies.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related lignans in drug development and quality control processes.
• Biochemical Research: Serves as a key intermediate or probe in studying enzyme inhibition, metabolic pathways, and biological signaling mechanisms.
• Natural Product Isolation & Synthesis: Acts as a benchmark for the isolation, purification, and total synthesis of complex natural products.
• Academic Research: Employed in university and institutional labs for pharmacological screening and structure-activity relationship (SAR) studies.
• Analytical Method Development: Essential for developing and validating chromatographic methods (HPLC, LC-MS) for complex plant extracts.

Basic Information

Product Name	(-)-Nortrachelogenin
CAS No.	34444-37-6
Molecular Formula	C20H20O7
Molecular Weight	372.37 g/mol
Synonyms	(-)-Nortrachelogenin; Nortrachelogenin; NSC 174939; 5,5'-Bis(1,3-benzodioxole)-2,2',3,3'-tetrahydro-4,4',7,7'-tetrol, (7'R,8R,8'R)-form; Justicidin C; 8-Hydroxyarctigenin; Arctigenin-8-ol; (7'R,8R,8'R)-5,5'-Bis(1,3-benzodioxole)-2,2',3,3'-tetrahydro-4,4',7,7'-tetrol
EINECS	Contact for details

Quality Control

Our (-)-Nortrachelogenin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, verified by advanced analytical techniques including HPLC and NMR. We adhere to relevant industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.