Description

Boc-Lys(Z)-Osu CAS NO 34404-36-9 is a high-purity, protected amino acid derivative widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over the lysine side chain during the construction of complex peptides and proteins. It is primarily utilized in the pharmaceutical, biotechnology, and life science research sectors for developing novel therapeutic agents, diagnostic tools, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal protecting groups.
• Solution-Phase Peptide Synthesis: Used in the synthesis of peptide fragments and small peptides in solution.
• Pharmaceutical Intermediate: Serves as a crucial raw material in the research and development of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific labeling or modification of peptides and proteins for diagnostic or therapeutic purposes.
• Biochemical Research: Employed in academic and industrial laboratories for studying protein structure, function, and interactions.
• Production of Custom Peptides: Used by CROs and CDMOs for the contract manufacturing of specialized peptide sequences.

Basic Information

Product Name	Boc-Lys(Z)-Osu
CAS No.	34404-36-9
Molecular Formula	C23H33N3O8
Molecular Weight	479.53 g/mol
Synonyms	Nα-Boc-Nε-Cbz-L-lysine N-hydroxysuccinimide ester; Nα-(tert-Butoxycarbonyl)-Nε-(benzyloxycarbonyl)-L-lysine N-succinimidyl ester; Boc-Lys(Z)-OSu; Boc-Lys(Cbz)-OSu; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid; N-Boc-N'-Cbz-L-lysine N-hydroxysuccinimide ester; Nα-Boc-Nε-Z-L-lysine OSu ester; Fmoc-Lys(Boc)-OH (Note: This is a related but different compound, often searched in conjunction)
EINECS	Contact for details

Quality Control

Our Boc-Lys(Z)-Osu is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and our quality systems support compliance with cGMP standards for pharmaceutical intermediates, ensuring reliable supply for critical research and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]D20	-15.0° to -18.0° (c=1 in DMF)
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.