Description

10-Bromodecanoic Acid Trimethylsilyl Ester is a high-purity, protected carboxylic acid derivative, primarily utilized as a versatile synthetic intermediate in advanced organic synthesis. Its core value lies in the combination of the reactive bromoalkyl chain and the silyl-protected carboxyl group, enabling precise, multi-step molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing complex molecules, such as bioactive compounds and liquid crystal materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those requiring long-chain fatty acid modifications or specific alkyl chain functionalization.
• Agrochemical Synthesis: Used in the production of specialized pesticides and herbicides where the bromo functionality allows for further coupling reactions.
• Liquid Crystal & Advanced Material Precursor: Serves as a monomer or intermediate in the creation of novel organic materials with specific mesogenic properties.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers, where the protected acid group can be selectively deprotected and further reacted.
• Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Negishi couplings to form carbon-carbon bonds.
• Bioconjugation & Probe Development: Useful in modifying biomolecules or creating fluorescent or affinity probes for biochemical research.

Basic Information

Product Name	10-Bromodecanoic Acid Trimethylsilyl Ester
CAS No.	34176-84-6
Molecular Formula	C₁₃H₂₇BrO₂Si
Molecular Weight	323.35 g/mol
Synonyms	Trimethylsilyl 10-bromodecanoate; 10-Bromodecanoic Acid TMS Ester; Decanoic acid, 10-bromo-, trimethylsilyl ester; TMS 10-Bromodecanoate; (10-Bromodecyloxy)trimethylsilane (common misnomer); Bromodecanoic Acid Trimethylsilyl Ester; Trimethyl(10-bromodecanoyloxy)silane
EINECS	Contact for details

Quality Control

Our 10-Bromodecanoic Acid Trimethylsilyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.