Description

Hexanoic Acid, 6-Bromo-, Trimethylsilyl Ester is a specialized organosilicon reagent featuring a bromohexanoate backbone protected by a trimethylsilyl (TMS) group. This compound is a critical synthetic intermediate, valued for its dual functionality as a protected carboxylic acid and an alkyl halide, enabling precise carbon chain elongation and functional group transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing functionalized hexanoic acid derivatives.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators requiring specific alkyl chain modifications.
• Organic Synthesis Reagent: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions for carbon-carbon bond formation.
• Material Science Precursor: Employed in the development of specialty polymers, liquid crystals, and surface-modifying agents.
• Peptide Mimetics & Bioconjugation: Facilitates the incorporation of lipophilic or reactive handles into peptide chains and bioconjugates.
• Protecting Group Strategy: The TMS ester acts as a temporary protecting group for the carboxylic acid, allowing orthogonal deprotection in multi-step syntheses.

Basic Information

Item	Detail
Product Name	Hexanoic Acid, 6-Bromo-, Trimethylsilyl Ester
CAS No.	34176-76-6
Molecular Formula	C9H19BrO2Si
Molecular Weight	267.24 g/mol
Synonyms	6-Bromohexanoic Acid Trimethylsilyl Ester; Trimethylsilyl 6-Bromohexanoate; 6-Bromohexanoic Acid TMS Ester; (6-Bromohexanoyloxy)trimethylsilane; TMS 6-Bromohexanoate; Bromohexanoic Acid Trimethylsilyl Ester; Hexanoic acid, 6-bromo-, 1-(trimethylsilyl) ester
EINECS	Contact for details

Quality Control

Our Hexanoic Acid, 6-Bromo-, Trimethylsilyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent hydrolysis of the silyl ester.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.