Description

(1Ar,4E,7S,7Ar,10As,10Br)-2,3,6,7,7A,8,10A,10B-Octahydro-7-Hydroxy-1A,5-Dimethyl-8-Methyleneoxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One is a complex, high-purity sesquiterpene lactone derivative with a unique oxireno-fused cyclodecane structure. This compound is valued for its sophisticated molecular architecture, which makes it a critical advanced intermediate or reference standard in specialized organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Reference Standard: Used in analytical laboratories for method development, calibration, and quality control of related complex natural products or synthetic analogs.
• Agrochemical Research: Investigated as a precursor for developing new plant growth regulators or bioactive agents with specific modes of action.
• Organic Synthesis: Employed in advanced methodological studies, such as cycloaddition reactions or stereoselective transformations, due to its intricate polycyclic framework.
• Natural Product Chemistry: Acts as a synthetic target or analog for studying the structure-activity relationships of sesquiterpene lactones found in nature.
• Material Science Research: Potential use as a specialty monomer or precursor for synthesizing polymers with unique thermal or optical properties.

Basic Information

Item	Details
Product Name	(1Ar,4E,7S,7Ar,10As,10Br)-2,3,6,7,7A,8,10A,10B-Octahydro-7-Hydroxy-1A,5-Dimethyl-8-Methyleneoxireno[9,10]Cyclodeca[1,2-B]Furan-9(1Ah)-One
CAS No.	34175-72-9
Molecular Formula	C15H18O4
Molecular Weight	262.30 g/mol
Synonyms	Parthenolide analog; Oxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one derivative; 7-Hydroxy-1a,5-dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one; Sesquiterpene lactone oxirane; [1aR-(1aα,4β,7α,7aβ,10aα,10bβ)]-2,3,6,7,7a,8,10a,10b-Octahydro-7-hydroxy-1a,5-dimethyl-8-methyleneoxireno[9,10]cyclodeca[1,2-b]furan-9(1aH)-one; Advanced parthenolide intermediate; Cyclodeca[1,2-b]furan-9(1aH)-one, 2,3,6,7,7a,8,10a,10b-octahydro-7-hydroxy-1a,5-dimethyl-8-methylene-, oxireno[9,10]-
EINECS	Contact for details

Quality Control

Every batch of this high-value intermediate is produced and analyzed under strict quality management protocols. We ensure identity, purity, and consistency through advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider inert gas purging or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.