Description

(+)-6,7,8,12B-Tetrahydro-12B-Hydroxy-10,11-Dimethoxy-6-Methyl-1,3-Dioxolo[4,5]Indeno[2,1-A][3]Benzazepin-13(5Bh)-One is a complex, chiral organic compound belonging to the benzazepine class, characterized by its fused polycyclic structure. This compound matters as a sophisticated chemical intermediate or reference standard for advanced research and development in medicinal chemistry. It is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers focused on developing novel therapeutic agents, particularly in the areas of central nervous system (CNS) and neurological disorders.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a reference compound or starting material for structure-activity relationship (SAR) studies and lead optimization.
• Analytical Standard: Employed as a high-purity standard for method development and validation in analytical laboratories (HPLC, LC-MS).
• Academic & Institutional R&D: Utilized in university and research institute projects exploring new chemical entities and their biological activities.
• Process Chemistry Development: Acts as a model compound for developing and scaling up complex asymmetric synthesis routes.
• Biochemical Research: Potential use in studying enzyme interactions or receptor binding assays due to its specific stereochemistry and functional groups.

Basic Information

Product Name	(+)-6,7,8,12B-Tetrahydro-12B-Hydroxy-10,11-Dimethoxy-6-Methyl-1,3-Dioxolo[4,5]Indeno[2,1-A][3]Benzazepin-13(5Bh)-One
CAS No.	34084-34-9
Molecular Formula	C22H23NO7
Molecular Weight	413.42 g/mol
Synonyms	(+)-Galanthamine N-Oxide; (12bR)-12b-Hydroxy-10,11-dimethoxy-6-methyl-5b,6,7,8,12b,13-hexahydro-1,3-dioxolo[4,5]indeno[2,1-a][3]benzazepin-13-one; Galanthamine Impurity F (Oxide); Galanthamine N-Oxide (enantiomer); UNII-2J4Q8Q786K; 2J4Q8Q786K; (12bR)-12b-Hydroxy-10,11-dimethoxy-6-methyl-5b,6,7,8,12b,13-hexahydro-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridin-13-one
EINECS	Contact for details

Quality Control

Our (+)-6,7,8,12B-Tetrahydro-12B-Hydroxy-10,11-Dimethoxy-6-Methyl-1,3-Dioxolo[4,5]Indeno[2,1-A][3]Benzazepin-13(5Bh)-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, which includes data from chromatographic and spectroscopic methods. Our quality commitment aligns with the standards expected for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.