Description

(1R)-1,2,3,4,4A,4Bα,5,6,7,8,8Aβ,9,10,10Aα-Tetradecahydro-1,4Aβ-Dimethyl-7-(1-Methylethylidene)-1-Phenanthrenecarboxylic Acid Methyl Ester is a high-purity, synthetically derived diterpenoid ester with a complex, fused-ring structure. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, particularly within pharmaceutical research and fine chemical manufacturing. It is primarily sought by R&D chemists and process development scientists working on novel therapeutic agents, natural product derivatives, and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the research and development of novel drug candidates, especially those with steroidal or terpenoid backbones.
• Organic Synthesis: Serves as a versatile chiral precursor for constructing complex polycyclic frameworks in academic and industrial laboratories.
• Natural Product Analog Synthesis: Used to create synthetic analogs of bioactive natural products for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Intermediate in the multi-step synthesis of high-value specialty chemicals and performance materials.
• Reference Standard: Provides a high-purity standard for analytical method development, quality control, and regulatory submissions in pharmaceutical development.

Basic Information

Product Name	(1R)-1,2,3,4,4A,4Bα,5,6,7,8,8Aβ,9,10,10Aα-Tetradecahydro-1,4Aβ-Dimethyl-7-(1-Methylethylidene)-1-Phenanthrenecarboxylic Acid Methyl Ester
CAS No.	33892-19-2
Molecular Formula	C22H34O2
Molecular Weight	330.51 g/mol
Synonyms	Methyl (1R)-1,2,3,4,4a,4bα,5,6,7,8,8aβ,9,10,10aα-tetradecahydro-1,4aβ-dimethyl-7-(1-methylethylidene)-1-phenanthrenecarboxylate; Methyl Abietate Isomer; Dehydroabietic Acid Methyl Ester (specific isomer); (1R)-Dehydroabietic Acid Methyl Ester; Diterpene Resin Acid Methyl Ester; 1-Phenanthrenecarboxylic Acid, 1,2,3,4,4a,4b,5,6,7,8,8a,9,10,10a-tetradecahydro-1,4a-dimethyl-7-(1-methylethylidene)-, methyl ester, (1R,4aR,4bS,10aR)-; Abietic Acid Derivative.
EINECS	Contact for details

Quality Control

Our (1R)-1,2,3,4,4A,4Bα,5,6,7,8,8Aβ,9,10,10Aα-Tetradecahydro-1,4Aβ-Dimethyl-7-(1-Methylethylidene)-1-Phenanthrenecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.