Description

Spiro[Bicyclo[3.1.0]Hexane-2,1-Cyclopropane], 5-Isopropyl-, (-)- (8Ci) is a high-purity, chiral spirocyclic organic compound characterized by its unique fused ring structure. This specialized intermediate is critical for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals where precise stereochemistry is required. It serves as a valuable building block for research chemists and process development scientists in fine chemical, pharmaceutical, and advanced material sectors seeking to introduce complex, three-dimensional molecular frameworks.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: Essential compound for methodological studies in organic chemistry, including cycloaddition and ring-opening reactions.
• Flavor & Fragrance Synthesis: Potential intermediate for creating complex terpenoid-like aroma molecules.

Basic Information

Product Name	Spiro[Bicyclo[3.1.0]Hexane-2,1-Cyclopropane], 5-Isopropyl-, (-)- (8Ci)
CAS No.	33889-88-2
Molecular Formula	C11H18
Molecular Weight	150.26 g/mol
Synonyms	(-)-5-Isopropylspiro[bicyclo[3.1.0]hexane-2,1'-cyclopropane]; (1S,5R)-5-(Propan-2-yl)spiro[bicyclo[3.1.0]hexane-2,1'-cyclopropane]; 5-Isopropylspiro[bicyclo[3.1.0]hexane-2,1'-cyclopropane], (-)-; Spiro compound 33889-88-2; 1,1'-(1-Methylethyl)spiro[cyclopropane-1,2'-bicyclo[3.1.0]hexane], (1'R,2'S,5'R)-rel-; Chiral Spirocyclic C11H18 Isomer
EINECS	Contact for details

Quality Control

Our Spiro[Bicyclo[3.1.0]Hexane-2,1-Cyclopropane], 5-Isopropyl-, (-)- (8Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided to guarantee consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.